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TOP NEWS: Ischemic Heart Disease Mortality and Morbidity Rates in Former Drinkers

Freitag 17. Dezember 2010 von htm

A Meta-Analysis.
Current abstainers from alcohol have been identified as an inadequate reference group in epidemiologic studies of the effects of alcohol, because inclusion of former drinkers might lead to overestimation of the protective effects and underestimation of the detrimental effects of drinking alcohol.
The authors’ objective in the current study was to quantify this association for ischemic heart disease (IHD).
Electronic databases were systematically searched for relevant case-control or cohort studies published from 1980 to 2010. Thirty-eight articles fulfilled the inclusion criteria, contributing a total of 5,613 IHD events and 12,097 controls among case-control studies and 1,387 events with combined endpoints and 7,183 events stratified by endpoint among 232,621 persons at risk among cohort studies.
Pooled estimates for the subset stratified by sex and endpoint showed a significantly increased risk among former drinkers compared with long-term abstainers for IHD mortality ( among men; relative risk = 1.25, 95% confidence interval: 1.15, 1.36; among women relative risk = 1.54, 95% confidence interval: 1.17, 2.03).
For IHD morbidity, the estimates for both sexes were close to unity and not statistically significant. Results were robust in several sensitivity analyses.
In future studies, researchers should separate former drinkers from the reference category to obtain unbiased effect estimates. Implications for the overall beneficial and detrimental effects of alcohol consumption on IHD are discussed below. (Source: Alcohol Reports, 12/17/10) Alcohol Reports 01/21/11 full report Comment: Here is the proof for what we wrote always when not specified „Abstainers“ were used to proof health benefits of alcohol consumption. This is one of the reasons those studies are not correct. This meta-analysis compared with long-term abstainers, not event with lifelong abstainers. The alcohol industry and its lobbies did it very clever that even the WHO admitted some positive effects. It should come back to it.

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Dieser Beitrag wurde erstellt am Freitag 17. Dezember 2010 um 12:11 und abgelegt unter Alcohol industry, Allgemein, Global, Health, Research, TOP NEWS, WHO. Kommentare zu diesen Eintrag im RSS 2.0 Feed. Die Kommentare sind derzeit geschlossen, aber sie können einen Trackback auf Ihrer Seite einrichten.

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