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Research: Alcohol Consumption at Midlife and Risk of Stroke

Donnerstag 5. Februar 2015 von htm

Original Contribution
Alcohol Consumption at Midlife and Risk of Stroke During 43 Years of Follow-Up
Cohort and Twin Analyses
Pavla Kadlecová, MSc,
Ross Andel, PhD,
Robert Mikulík, PhD,
Elizabeth P. Handing, BA and
Nancy L. Pedersen, PhD
STROKE AHA.114.006724
Published online before print January 29, 2015, doi: 10.1161/STROKEAHA.114.006724

From the International Clinical Research Center, Neurology Department, St. Anne’s Hospital, Brno, Czech Republic (P.K., R.A., R.M.); School of Aging Studies, University of South Florida, Tampa (R.A., E.P.H.); Department of Neurology, St. Anne’s University Hospital and Medical Faculty of Masaryk University, Brno, Czech Republic (R.M.); Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (N.L.P.); and Department of Psychology, University of Southern California, Los Angeles (N.L.P.).
Correspondence to Pavla Kadlecová, MSc, Pekařská 53, 656 91 Brno, Czech Republic. E-mail kadlecovap{at}fnusa.cz

Abstract

Background and Purpose—Although alcohol–stroke association is well known, the age-varying effect of alcohol drinking at midlife on subsequent stroke risk across older adulthood has not been examined. The effect of genetic/early-life factors is also unknown. We used cohort and twin analyses of data with 43 years of follow-up for stroke incidence to help address these gaps.

Methods—All 11 644 members of the population-based Swedish Twin Registry born 1886 to 1925 with alcohol data aged ≤60 years were included. The interaction of midlife alcohol consumption by age at stroke was evaluated in Cox-regression and analyses of monozygotic twins were used. Covariates were baseline age, sex, cardiovascular diseases, diabetes mellitus, stress reactivity, depression, body mass index, smoking, and exercise.

Results—Altogether 29% participants developed stroke. Compared with very-light drinkers (<0.5 drink/d), heavy drinkers (>2 drinks/d) had greater risk of stroke (hazard ratio, 1.34; P=0.02) and the effect for nondrinkers approached significance (hazard ratio, 1.11; P=0.08). Age increased stroke risk for nondrinkers (P=0.012) and decreased it for heavy drinkers (P=0.040). Midlife heavy drinkers were at high risk from baseline until the age of 75 years when hypertension and diabetes mellitus grew to being the more relevant risk factors. In analyses of monozygotic twin-pairs, heavy drinking shortened time to stroke by 5 years (P=0.04).

Conclusions—Stroke-risk associated with heavy drinking (>2 drinks/d) in midlife seems to predominate over well-known risk factors, hypertension and diabetes, until the age of ≈75 years and may shorten time to stroke by 5 years above and beyond covariates and genetic/early-life factors. Alcohol consumption should be considered an age-varying risk factor for stroke.

Kategorie: adults, Allgemein, consumption, Education, English Website, Global, Health, mortality, Non-communicable diseases, Research, Statistics | Keine Kommentare »

Ca 9 million children are affected by their parents’ problems with alcohol

Donnerstag 14. Februar 2013 von htm

If you are interested in this problem please go to this link.

Wenn Sie an diesem Thema interessiert sind, sollten Sie diesen Link benützen. (englisch)

Kategorie: Addiction, adults, Allgemein, Children, Documents, Jugend, Parents, Youth | Keine Kommentare »

A Prospective Cohort Study of the Prevalence of Growth, Facial, and Central Nervous System Abnormalities in Children with Heavy Prenatal Alcohol Expos

Donnerstag 26. Juli 2012 von htm

Most children who are exposed to large quantities of alcohol in utero do not develop fetal alcohol syndrome (FAS). Population-based prospective data on the risk of developing components of fetal alcohol spectrum disorders (FASD), however, are limited.

This was a prospective cohort study of 9,628 women screened during their first prenatal appointment in Chile, which identified 101 who consumed at least 4 drinks/d (exposed) matched with 101 women with no reported alcohol consumption during pregnancy (unexposed). Detailed alcohol consumption data were collected during the pregnancy. Children were evaluated up to 8.5 years of age by clinicians masked to exposure status. …

After exposure to heavy alcohol consumption during pregnancy, 80% of children had 1 or more abnormalities associated with alcohol exposure. Patterns of alcohol use that posed the greatest risk of adverse outcomes were binge drinking and high total weekly intake. Functional neurologic impairment occurred most frequently and may be the only sign to alert physicians to prenatal alcohol exposure. ….
(Source: Alcohol Reports, 07/23/12) onlinelibrary.wiley.com, 07/23/12

Kategorie: adults, Allgemein, Binge Drinking, Children, consumption, Fetal alcohol syndrome etc., Gender, Global, Health, Parents, Research | Keine Kommentare »

Drinking alcohol, even in moderation, ‘a dementia risk’

Mittwoch 18. Juli 2012 von htm

The findings, presented at an international conference, challenge the notion that some alcohol could be good for ageing brains.

People who stick to recommended alcohol limits are still at risk, as well as bingers and heavy drinkers, according to the work.

The study tracked the health over 20 years of 1,300 women in their mid-60s.

The risk, ranging from mild cognitive impairment to full blown dementia, was higher among those who reported drinking more alcohol.

Women who switched from abstinence to drinking over the course of the study also increased their risk.

Those who drank alcohol “in moderation”, meaning seven to 14 alcoholic drinks a week, were also more likely to develop problems with memory and brain functioning that can be a warning sign of future dementia. …
(Source: Google alcohol news, 07/18/12) (news-ad-hoc.de, 18.7.12) bbc.co.uk, 07/18/12

Kategorie: adults, Allgemein, Binge Drinking, consumption, drinking guidelines, Gender, Global, Health, morbidity, Publications, Research, safe level, Statistics | Keine Kommentare »

USA: Increase in Cigarette Prices Leads to Rise in Binge Drinking Among Young Adults

Mittwoch 18. Juli 2012 von htm

The study found increased cigarette prices due to taxes did not decrease smoking rates in people under 30, The Atlantic reports.

The researchers based their findings on data from the 2001-2006 Behavioral Risk Factor Surveillance System surveys, which included 1.3 million people. They found increases in state cigarette prices were associated with increases in current drinking among people ages 65 and older, and binge and heavy drinking among those ages 21 to 29. They found reductions in smoking among adults ages 30 to 64, drinking among those ages 18 to 20, and binge drinking among those 65 and older.

“Researchers, practitioners, advocates, and policymakers should work together to understand and prepare for these unintended consequences of tobacco taxation policy,” the researchers wrote in the journal Substance Abuse Treatment, Prevention, and Policy.
(Source: Join Together, 07/17/12)

Kategorie: adults, Allgemein, Binge Drinking, consumption, Global, Non-communicable diseases, Other Drugs, Price, Publications, Research, Statistics, Watchdogs, Youth | Keine Kommentare »

AU: Sports get $25m to curb binge drinking

Samstag 30. Juni 2012 von htm

TWELVE sports associations will become teetotal when it comes to alcohol sponsorship after a $25 million deal with the government.

The groups have struck a deal to promote safe alcohol consumption by adults, alcohol-free sporting environments for minors and to reduce alcohol promotion in their codes.

But the AFL and NRL were not part of the deal. Those that do have a stake include national associations for soccer, basketball, netball, swimming, cycling, hockey, athletics, skateboarding, volleyball, equestrian, triathlon and canoeing. They will be precluded from sponsorship that promotes alcohol consumption as it would be in conflict with the health campaign message of Be the Influence, Tackling Binge Drinking.

(Source: Harvard World Health News, 06/29/12) smh.com.au, 06/24/12

Kategorie: adults, Advertising, Allgemein, Documents, Global, Parliaments / Governments, Politics, Prevention, societal effects, Sports, Youth | Keine Kommentare »

USA: Pennsylvania Alcohol Privatization Off the Table

Donnerstag 28. Juni 2012 von htm

State Control of Alcohol: Protecting the Public’s Health

Pennsylvania Republican House Majority Leader Michael Turzai recently gave up the fight to privatize liquor sales in the state, at least for the moment. The battle to privatize Pennsylvania’s 620 state-owned liquor and wine stores, and to allow the sale of alcohol by non-state retailers, has been raging in Pennsylvania for several years. In 2010, then-gubernatorial candidate (now governor) Tom Corbett made alcohol privatization a key part of his election campaign. Since then, advocates for state control and new research findings regarding its effectiveness have helped fight off the ill-fated plan.

When the 21st Amendment repealed national prohibition in 1933, states became responsible for
regulating alcoholic beverages. While many states decided to license private businesses to sell alcohol,
18 states chose to control alcohol sales themselves. The goal was to provide a legal way for people
to obtain alcohol, but also encourage moderate consumption by reducing economic incentives for
maximum sales.

States that currently have monopolies over control either beer, wine, or spirits (or some combination)
are: Alabama, Idaho, Iowa, Maine, Michigan, Mississippi, Montana, New Hampshire, North Carolina,
Ohio, Oregon, Pennsylvania, Utah, Vermont, Virginia, Washington, West Virginia, and Wyoming. In
addition, Montgomery County, Maryland controls spirits, beer, and wine (the only jurisdiction that
controls all three). …
(Source: Alcohol Justice, 06/27/12)

Kategorie: Addiction, adults, Alcohol industry, Alcohol taxes, Allgemein, Availability, consumption, Driving under the Influence, Global, Health, mortality, Parliaments / Governments, Politics, Prevention, Research, societal effects, Statistics, Watchdogs, Youth | Keine Kommentare »

‘Statistics on Alcohol: England 2012′ confirms continuing upward admissions trend

Mittwoch 6. Juni 2012 von htm

The latest annual statistics on alcohol for England 2012 have been released by the ONS, confirming a continuing rise in alcohol-related and primary alcohol attributable hospital conditions. Alcohol-related admissions rose 11% on the previous year with primary diagnosis conditions up 2.1%. Ns_logo

This comes despite falls since 2004 in the proportion of adults reporting drinking alcohol. Continuing admissions – many being long term conditions – are thought to be linked to decades of rising consumption prior to 2004. Additionally indications that amongst some groups, those who are drinking are drinking more.

Some key facts from the report include:

A 2.1% increase in primary diagnosis alcohol conditions (198,900 for 2010/11) since the previous year and a 40% increase since 2003 (142,000).
A 11% increase on alcohol-related admissions (based on attributable fractions) totalling 1,168,300 for 2010/11.This is more than twice as many as in 2002/03 (510,700). …
(Source: Alcohol Policy UK, 06/5/12)

Kategorie: Addiction, adults, Allgemein, Binge Drinking, Children, consumption, Gender, Global, Health, Research, Social Costs, societal effects, Statistics, Treatment, Watchdogs, Youth | Keine Kommentare »

UK: One in eight deaths before retirement is caused by alcohol, study finds

Dienstag 22. Mai 2012 von htm

One in eight deaths of UK adults under the age of 64 is caused by alcohol, an international conference on tackling problem drinking has heard.

The social cost of alcohol abuse has been estimated to be £240 a year for each European, with the annual bill for the NHS alone being £2.7 billion.

A major conference of addiction specialists from across the world is meeting at Newcastle University and organisers have called for England to follow Scotland and set a minimum price per unit.

They have also demanded a ban on advertising alcohol.
Too easy: Prof Eileen Kaner from Newcastle University said the government had to be bolder about tackling cheap alcoholl

In Europe, alcohol consumption is more than twice the global average and it represents the biggest addiction in the UK, greater than any illegal drug or gambling.

(Source: Alcohol Reports, News, 05/21/12) dailymail.co.uk, 05/16/12

Kategorie: Addiction, adults, Advertising, Alerts, Allgemein, Availability, Binge Drinking, consumption, Events, Global, Health, mortality, Parliaments / Governments, Politics, Prevention, Price, Research, Social Costs, societal effects | Keine Kommentare »

THE GLOBE – Issue 2 – 2012

Freitag 11. Mai 2012 von htm

In this issue:

NCD Alcohol Target Dropped to Placate Drinks Industry

Corporate Social Responsibility initiatives used “to undermine alcohol control policies”

Free trade agreements “threaten public health”

Global Alcohol Policy Conference – DECLARATION

Adults in Europe consume three standard alcoholic drinks per day on average New report on alcohol in European Union
and more….
THE GLOBE No. 2, 2012

Kategorie: Addiction, adults, Advertising, Alcohol industry, Allgemein, Availability, consumption, Development, Events, Global, Health, Parliaments / Governments, Politics, Prevention, Price, Publications, Research, Watchdogs | Keine Kommentare »

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